New to the Mac? Check out TUAW's Mac 101

AOL Money & Finance

Pfizer shakes up drug development staffing

More

The boomer generation is limping toward retirement with pockets full of cash and bodies full of ailments, putting any drug company with top-drawer medications and solid patents in line for a windfall. Today's shakeup at Pfizer's (NYSE: PFE) drug-pipeline management, with the announced retirement of R&D president John LaMattina [subscription required], suggests the company isn't happy with the lack of success in restocking its shelves.

Pfizer, the largest pharmaceutical company in the world, realized 64% of its 2006 revenue from its top nine sellers. Unfortunately, the patents for those brands are rapidly expiring:

  • Norvasc: 2007
  • Zyrtec: 2007
  • Lipitor: 2010
  • Viagra: 2012
  • Detrol: 2012
  • Cardura X: 2008

Pfizer's patent on Zithromax expired in 2005, Zoloft in 2006, and the Cox-2 drug Celebrex has been caught up in controversy over the safety of that class of drug.

The company's fortunes suffered a setback recently; its best hope for revenue pickup once the Lipitor patent expires, torcetrapib, failed in trials. While the company has brought new cancer, diabetes and smoking-cessation drugs to market, it'll need some more big hitters to replace the lost income of the top nine when they come off patent.

With Pfizer's poor first-quarter report -- EPS was down from $0.56 a year ago to $0.48 -- the market has shown skepticism about the company's direction. The staff shakeup, along with ongoing cost-cutting measures to meet CEO Jeffrey Kindler's plan to shave $500 million or more from the bottom line this year, should reassure shareholders the company isn't pleased with business as usual. This may also be a reason to expect Pfizer to step outside the organization to draft McLa Mattina's replacement.

Reader Comments (Page 1 of 1)

Symbol Lookup
IndexesChangePrice
DJIA+4.768,183.17
NASDAQ+5.381,752.55
S&P 500+3.12882.68

Last updated: July 09, 2009: 08:00 PM

BloggingStocks Exclusives

Hot Stocks

DailyFinance Headlines

Latest from BloggingBuyouts

TheFlyOnTheWall.com Headlines

BioHealth Investor Headlines

WalletPop Headlines

My Portfolios

Track your stocks here!

Find out why more people track their portfolios on AOL Money & Finance then anywhere else.

BloggingStocks Partners

More from AOL Money & Finance

WalletPop Headlines