Several stocks made new 52-week highs today on large volume.

Adams Respiratory Therapeutics, Inc. (NASDAQ: ARXT): Personal care products maker Reckitt Benckiser made a buy-out offer. Shares moved up to $59.30 against a 52-week low of $27.25.

MGI Pharma, Inc. (NASDAQ: MOGN): Japanese pharmaceutical maker Eisai will buy the company. Shares rose to $40.23 compared to 52-week low of $16.98.

Millennium Pharmaceuticals, Inc. (NASDAQ: MLNM): This company's late stage cancer drug shows promise. The company hit $16.62, well up from 52-week low of $9.49.

Canadian Solar Inc. (NASDAQ: CSIQ): A new contract for peer LDK Solar Co., Ltd. (NYSE: LDK) pulled the entire sector higher. Canadian Solar hit $24.83 against a 52-week low of $6.50.

DynCorp International Inc. (NYSE: DCP): A new Army contract boosted shares to $25.97, compared with a 52-week low of $13.51.

Douglas A. McIntyre is an editor at 247wallst.com.

Main market news here: Before the bell: UBS announces $10 billion in write-downs

Citigroup (NYSE: C)'s board is meeting early this week and could name former Morgan Stanley (NYSE: MS) executive Vikram Pandit as its next CEO, following Chuck Prince's resignation last month.

Private equity firm Blackstone (NYSE: BX) is expected to join with China's sovereign wealth fund in a bid for mining firm Rio Tinto (NYSE: RIO). Blackstone's bid follows a $140 billion offer from BHP Billiton (NYSE: BHP), which Rio Tinto rejected. If Rio Tinto accepted any bid from Blackstone, the private equity house is expected to divide up Rio Tinto's assets.

In an unprecedentedly large overseas acquisition in Japanese pharma, Eisai Co. of Japan announced a $3.9 billion deal to buy Minnesota drug maker MGI Pharma (NASDAQ: MOGN) to bolster its cancer treatment efforts.

MOST NOTEWORTHY: The U.S. clean energy sector, MGI Pharma, Apple and Kosan Biosciences were today's noteworthy initiations:

• Morgan Stanley initiated the U.S. clean energy sector with an Attractive view. The analyst assumed coverage of First Solar (NASDAQ: FSLR), Fuel Tech (NASDAQ: FTEK) and SunPower Corporation (NASDAQ: SPWR) with Overweight ratings and EnerNOC, Inc (NASDAQ: ENOC) with an Underweight rating.
  
• Banc of America started shares of MGI Pharma (NASDAQ: MOGN) with a Buy rating and $45 target, as they expect sales growth in 2008 to be driven by Aquavan, which they view as an underappreciated asset, and potential survival data for Dacogen.
  
• Soleil believes Apple (NASDAQ: AAPL) could nearly double its PC market share to between 5.5% and 6% over the next five years. The firm started shares with a Buy rating and $200 target.
  
• Roth Capital initiated Kosan Biosciences (NASDAQ: KOSN) with a Buy rating and $10 target, as they are positive on the company's Hsp90 program and expect an NDA filing as early as 2009 in the relapsed-refractory settings.

OTHER INITIATIONS:

• KeyBanc Capital initiated CastlePoint Holdings (NASDAQ: CPHL) with a Buy rating and $16 target.
  
• Time Warner Telecom (NASDAQ: TWTC) was started at Cowen with an Outperform rating.
  
• Jefferies resumed coverage of Windstream (WIN) with a Hold rating and $16 target and Embarq Corporation (NYSE: EQ) with a Buy rating and $68 target.