Analyst upgrades:

• Oppenheimer upgraded Genzyme (NASDAQ: GENZ) to Outperform from Perform on expectations that upcoming regulatory events, mainly approvals of Mozobil and 2,000L Myozyme, will serve as positive catalysts.
  
• Ladenburg analyst Dick Bove raised Bank of New York (NYSE: BK) to Buy from Neutral as he now believes the Russian lawsuit is turning in the bank's favor and is no longer a significant risk.
  
• Societe Generale upgraded UBS (NYSE: UBS) to Buy from Hold on valuation and the company's deal with the Swiss government.
  
• Bed Bath & Beyond (NASDAQ :BBBY) was upgraded to Market Perform from Underperform at Friedman Billings.
  
• RC2 Corp (NASDAQ: RCRC) was lifted at Wachovia to Outperform from Market Perform.
  
• Cintas (NASDAQ: CTAS) was upgraded to Hold from Sell at Citigroup.

Analyst downgrades:

Analyst upgrades:

• Goldman upgraded shares of British Sky Broadcasting (NYSE: BSY) to Buy from Neutral and added the company to the Conviction Buy List as they find the stock oversold at current levels.
  
• Goldman also added Publicis (OTC: PUBGY) to the Conviction Buy List and upgraded shares to Buy from Neutral as they find the stock cheap at current levels.
• Oneok (NYSE: OKE) was upgraded to Overweight from Equal Weight at Lehman.
  
• UBS raised Wimm-Bill-Dann Foods (NYSE: WBD) to Buy from Neutral.

Analyst downgrades:

• Baird downgraded Amylin Pharma (NASDAQ: AMLN) to Neutral from Outperform and said they are incrementally more cautious on the commercial performance of Amylin's Byetta following the yesterday's update. Amylin's target was lowered to $27 from $37. Soleil recommends investors avoid Amylin with the disclosure last night of four additional cases of mortality associated with pancreatitis in patients who were on Byetta. The firm cut shares to Sell from Hold and lowered their target to $20 from $25.
  
• Citigroup downgraded shares of AMR Corp. (NYSE: AMR) to Sell from Hold on valuation as they find the stock expensive following the recent run-up. The firm raised their target to $9 from $6.70 to reflect the drop in crude prices.
  
• J Crew (NYSE: JCG) was downgraded to Hold from Buy at Brean Murray following the weak Q2 report and guidance.
• JMP Securities downgraded Quality Systems (NASDAQ: QSII) to Market Perform from Outperform.
  
• National Grid (NYSE: NGG) was lowered to Equal Weight from Overweight at Lehman.

Analyst initiations:

MOST NOTEWORTHY: Alcoa, Publicis Groupe and Fresenius were today's noteworthy downgrades:

• JP Morgan downgraded shares of Alcoa (NYSE: AA) to Neutral from Overweight as they do not believe the company is a takeover target. The firm thinks investors could be disappointed with the new CEO's strategic direction as well as near-term earnings.
  
• Societe Generale cut Publicis (OTC: PUBGY) to Sell from Buy on valuation following the recent rally and macroeconomic concerns.
  
• UBS downgraded Fresenius (NYSE: FMS) to Neutral from Buy citing valuation, but added shares to its Short-Term Buy list citing potential upward EPS revisions when the company reports on July 3.

OTHER DOWNGRADES:

• Annaly Capital (NYSE: NLY) and Microchip (NASDAQ: MCHP) were lowered to Neutral from Overweight at JP Morgan.
  
• Soleil downgraded Steris (NYSE: STE) to Sell from Hold.
  
• Goldman added National Grid (NYSE: NGG) and Marshall & Ilsley (NYSE: MI) to its Conviction Sell List and removed Las Vegas Sands (NYSE: LVS) from the Conviction Buy List.

MOST NOTEWORTHY: National Grid, Shire Plc, On Semiconductor and Enbridge were today's noteworthy upgrades:

• Deutsche Bank upgraded shares of National Grid (NYSE: NGG) to Buy from Hold as they believe the Keyspan deal will be positive for shareholders.
• Goldman upgraded shares of Shire Plc (NASDAQ: SHPGY) to Buy from Neutral and added the stock to their Conviction Buy List on valuation and expected gains in the ADHD market.
  
• On Semiconductor (NASDAQ: ONNN) was upgraded to Outperform from Market Perform at Wachovia on valuation.
  
• Enbridge Inc (NYSE: ENB) was raised to Sector Outperformer from Sector Performer at CIBC World Markets, as the firm sees an attractive 3-year return potential as new projects come into service and expects the stock's relative underperformance to come to an end.

OTHER UPGRADES:

• Visteon Corporation (NYSE: VC) was upgraded to Neutral from Sell at Goldman Sachs.
  
• RSC Holdings (NYSE: RRR) and Greenfield Online Inc (NASDAQ: SRVY) were upgraded to Overweight from Equal Weight at Lehman Brothers.
  
• Lockheed Martin Corporation (NYSE: LMT) was raised to Buy from Neutral at Merrill Lynch.
  
• Stifel upgraded Health Care REITs, including Healthcare Realty Trust (NYSE: HR), LTC Properties Inc (NYSE: LTC) and Ventas Inc (NYSE: VTR), to Buy from Hold.