Disney (NYSE: DIS) soared to the number-one spot this past weekend with its new Pixar project, Up. The computer cartoon grossed roughly $68 million at domestic theaters as of early estimates, according to Boxofficemojo.
Disney took a lot of thunder away from News Corp. (NYSE: NWS) and its Ben Stiller comedy/fantasy Night at the Museum: Battle of the Smithsonian. That movie dropped to second place, taking in about $25 million.
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It was a busy weekend at the box office. The Memorial Day holiday period is a time when studios try to set a good financial tone for their summer slates. 

