MOST NOTEWORTHY: British American Tobacco, Vertex Pharma and YRC Worldwide were today's noteworthy downgrades:

• ABN Amro downgraded shares of British American Tobacco (AMEX: BTI) to Hold from Buy on valuation, as they view shares as fairly valued following the strong performance in 2007.
  
• Wachovia lowered its rating on Vertex Pharma (NASDAQ: VRTX) to Underperform from Market Perform citing the potential push out of the telaprevir market launch to 2012 from 2010, which will allow the competition to grab share.
  
• The firm also downgraded YRC Worldwide (NASDAQ: YRCW) to Underperform from Market Perform, as they have little confidence in any material near-term improvement for the company.

OTHER DOWNGRADES:

• Bear Stearns downgraded Murphy Oil (NYSE: MUR) to Peer Perform from Outperform.
  
• UBS downgraded BG Group (OTC: BRGYY) to Neutral from Buy.
  
• Morgan Stanley downgraded Stancorp Financial (NYSE: SFG) to Neutral from Buy.

My recent Investing in Oregon post took a look at some companies that the Motley Fool had featured in its investigation of investment opportunities in the Beaver State, including Precision Castparts Corp. (NYSE: PCP), StanCorp Financial Group Inc. (NYSE: SFG), FLIR Systems Inc. (NASDAQ: FLIR), and Columbia Sportswear Co. (NASDAQ: COLM).

But the Motley Fool article also mentioned that one of the most prominent business influences in Oregon wasn't even headquartered in the state: semiconductor giant Intel Corp. (NASDAQ: INTC) from Santa Clara, California. It also included mention of four Oregon-based businesses that provided support for Intel: Tektronix Inc. (NYSE: TEK), Mentor Graphics Corp. (NASDAQ: MENT), Triquint Semiconductor Inc. (NASDAQ: TQNT), and Electro Scientific Industries Inc. (NASDAQ: ESIO). One could imagine that Intel's impressive earnings report this week should have been good news for these supporting companies.

Beaverton-based Tektronix, widely known as Tek, is one of the leading makers of test and measurement equipment, such as digital multimeters, logic analyzers, and curve tracers, and oscilloscopes. Tek will win its seventh technical Emmy this year. Tek beat Wall Street expectations in its previous three quarters, reporting earnings per share of 40 cents for its first quarter FY2008. But the consensus of analysts surveyed by Thomson Financial was to hold shares of Tek. The share price reached a 52-week high of $37.95 on Monday when it was announced that Danaher Corp. (NYSE: DHR) will acquire Tek. Tool and equipment maker Danaher just announced record third quarter results.

The end of Oregon Trail may not be the trapping and logging region that it once was, but the Beaver State still has a thriving agriculture sector, including such products as potatoes, apples, hops, and hazelnuts (more than 90% of domestic production of hazelnuts). But the Pacific Northwest is known today as a high-tech region, with growth through both domestic relocation and foreign immigration. The lack of a sales tax in Oregon probably doesn't hurt when it comes to attracting investment and labor.

When the Motley Fool investigated investment opportunities in Oregon earlier this year, first on their list was, of course, Oregon's largest public company, Beaverton-based Nike Inc. (NYSE: NKE), the world's largest shoemaker. We pretty regularly cover Nike here at BloggingStocks. The Motley Fool also took a look at Precision Castparts Corp. (NYSE: PCP), StanCorp Financial Group Inc. (NYSE: SFG), FLIR Systems Inc. (NASDAQ: FLIR), and Columbia Sportswear Co. (NASDAQ: COLM).

MOST NOTEWORTHY: Amgen, Inc (AMGN), Secure Computing Corp (SCUR), Advanced Micro Devices (AMD) and Level 3 Communications (LVLT) were some of today's more notable downgrades:

• UBS downgraded shares of Amgen Inc (NASDAQ: AMGN) to Reduce from Neutral as the firm believes most Medicare carriers will drop reimbursement for Aranesp in certain types of anemia due to safety concerns.

• Goldman Sachs cut Secure Computing Corp (NASDAQ: SCUR) to Sell from Neutral, citing valuation.

• Thomas Weisel believes Advanced Micro Devices (NYSE: AMD) will have a difficult time regaining lost channel share from Intel (INTC) without additional price cuts, downgrading shares to Market Weight to Overweight.

• Buckingham cut Level 3 Communications (NASDAQ: LVLT) to Accumulate from Strong Buy on valuation.

OTHER DOWNGRADES:

• Deutsche Bank downgraded shares of Edison International (NYSE: EIX) to Hold from Buy.

• Wachovia downgraded shares of Countrywide Financial Corp (NYSE: CFC) to Underperform from Market Perform on concerns that subprime weakness has spread to other sectors of the residential mortgage market.

• Ferris Baker Watts downgraded shares of Comstock Homebuilding (NASDAQ: CHCI) to Hold from Buy to reflect the uncertainty regarding the company's lender relationships and homebuilding market outlook.

• Citigroup downgraded shares of StanCorp Financial Group (NYSE: SFG) to Hold from Buy on valuation and recommends swapping money into Assurant, Inc (AIZ).

• JP Morgan cut AngloGold Ashanti Ltd (NYSE: AU) to Underweight from Neutral.

Analyst summaries provided by TheFlyOnTheWall.com (subscription required).