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FDA Approves Generic Cancer Treatment from Hospira

HSP logoHospira (HSP - option chain) shares are rising today after the company announced that the FDA has approved its generic cancer treatment docetaxel. The brand-name drug it will compete against, Sanofi-Aventis' (SNY) Taxotere, had sales of $1.2 billion in 2010. If you think that the stock won't fall by too much in the coming months, then now could be a good time to look at a bullish hedged trade on HSP.

HSP opened this morning at $53.66. So far today the stock has hit a low of $53.55 and a high of $56.00. As of 12:05, HSP is trading at $54.65 up $1.02 (1.9%). The chart for HSP looks bullish and S&P gives HSP a positive 4 STARS (out of 5) buy ranking.

Continue reading FDA Approves Generic Cancer Treatment from Hospira

Incyte Soars on Blood Cancer Treatment Results

Incyte logoIncyte (INCY - option chain) shares are rising today after the company reported positive results from a Phase 3 study of its bone-marrow treatment. INCY said it is on pace to submit a new-drug application for the treatment during the second quarter of 2011. If you think that the stock won't fall by too much in the coming months, then now could be a good time to look at a bullish hedged trade on INCY.

INCY opened this morning at $15.93. So far today the stock has hit a low of $15.70 and a high of $16.39. As of 11:55, INCY is trading at $16.28 up $1.10 (7.3%). The chart for INCY looks bullish.

Continue reading Incyte Soars on Blood Cancer Treatment Results

Is Genoptix Buyout Bait?

Over the past week, the medical diagnostic instrument market has heated up. On Friday, there was a report that Beckman Coulter (BEC) was seeking a buyer. On the news, the shares spiked 27%

Now there may be another deal. Genoptix (GXDX), which develops cancer testing equipment, appears to also be on the selling block. It looks like the process is in its early stages.

Continue reading Is Genoptix Buyout Bait?

Dendreon Sinks on Lengthy Medicare Timeline

DNDN logoDendreon (DNDN - option chain) stock is trading lower today after Medicare administrators said they will take a full year to determine whether the government should cover DNDN's expensive prostate cancer treatment Provenge. If you think this stock won't be rising too far in the coming months, then it could be a good time to look at a bearish hedged play on DNDN, which will give us a chance to make money on DNDN while this decision remains pending.

This morning, DNDN opened at $28.18. So far today the stock has hit a high of $29.76 and a low of $28.01. As of 12:10, DNDN is trading at $28.87, down $3.46 (-10.7%). The chart for DNDN looks bearish.

Continue reading Dendreon Sinks on Lengthy Medicare Timeline

Pfizer Sees Some Disappointing Study Results

Late Thursday, Pfizer (PFE) announced that two of its late-stage studies of an approved kidney cancer drug failed to treat breast cancer significantly. Reportedly, two studies of kidney cancer drug Sutent did not show a significant benefit to advanced breast cancer patients when combined with chemotherapy.

This news is definitely a setback for PFE, as it was hoped that Sutent could demonstrate a significant benefit when combined with chemotherapy as opposed to treatment by chemotherapy alone.

Continue reading Pfizer Sees Some Disappointing Study Results

Celgene Remains in an Uptrend

Celgene Corp.'s (CELG) stock has encountered resistance at $58, but I'm nevertheless reiterating my buy rating for the company's shares, first recommended on June 19, 2009, at a price of $46.94. Here's why:

Look for Celgene's FY2010 revenue to increase 20-23%, on top of a likely a 15-20% rise in FY2009, boosted by cancer treatments Revlimid's and Vidaza's sales. Further, pipeline candidates to treat psoriasis and small cell lung cancer are approaching late-stage study.

Continue reading Celgene Remains in an Uptrend

Celgene Blood Cancer Drug Found Effective

CELG logoCelgene (CELG - option chain) shares are rising today after a late-stage study of its blood cancer drug Revlimid was found to be so effective that the study was stopped early. If you think that the stock won't fall by too much in the coming months, then now could be a good time to look at a bullish hedged trade on CELG.

CELG opened this morning at $54.36. So far today the stock has hit a low of $54.02 and a high of $56.16. As of 12:15, CELG is trading at $55.81 up @5.19 (10.3%). The chart for CELG looks bullish and S&P gives CELG a positive 5 STARS (out of 5) strong buy ranking.

Continue reading Celgene Blood Cancer Drug Found Effective

Spectrum Pharma (SPPI) drops on cancer drug setback

SPPI logoSpectrum Pharmaceutical (NASDAQ: SPPI - option chain) stock is trading lower today after the company received a Complete Response letter from the FDA regarding FUSILEV, its treatment for advanced metastatic colorectal cancer. The FDA said the company did not demonstrate that FUSILEV is non-inferior to leucovorin in its supplemental New Drug Application. If you think this stock won't be rising too far in the coming months, then it could be a good time to look at a bearish hedged play on SPPI.

This morning, SPPI opened at $4.98. So far today the stock has hit a high of $5.44 and a low of $4.82. As of 12:00, SPPI is trading at $5.12, down $1.09 (-17.6%). The chart for SPPI looks neutral.

Continue reading Spectrum Pharma (SPPI) drops on cancer drug setback

U.S. trio wins Nobel Prize for Medicine; Merck to develop vaccine

First, who are the Nobel Prize winners? Why is their research so important in the areas of aging and cancer detection?

Three Americans won the Nobel Prize for medicine. They are Elizabeth Balckburn, Jack Szostak and Carol Greider. Balckburn is with the University of California, San Francisco, Greider is with Johns Hopkins School of Medicine in Baltimore and Szostak is at the Harvard Medical School.


Continue reading U.S. trio wins Nobel Prize for Medicine; Merck to develop vaccine

Eli Lilly to restructure, bet on drug portfolio

Pharmaceutical company Eli Lilly & Co. (NYSE: LLY) is planning to cut 5,500 jobs over the next few years and reorganize into five business units. The company is looking to reduce costs and accelerate how long it takes new drugs to get to market, especially as its top performers see their patents expire. This translates to a workforce reduction of close to 14% – to 35,000. This measure doesn't include new positions in emerging markets with high potential and Japan.

The company hopes to cut as much as possible through attrition and retirements – and it would not indicate how many other positions would have to be cut.

Eli Lilly's goal is to slash its annual cost by $1 billion during this restructuring. The new business units will be: cancer, diabetes, established markets, emerging markets and Elanco, which is its animal health business. This is a change from the existing functional model, which separates U.S. and global marketing for each drug in the company's portfolio. Through the new structure, Lilly says, drug development and marketing will be tied more closely.

Continue reading Eli Lilly to restructure, bet on drug portfolio

Delcath jumps 18% as its chemotherapy agent gets orphan drug status

Delcath Systems Inc. (NASDAQ: DCTH), which in pre-market trading shot up 48%, closed the trading session up 18% to close at $3.60 after the FDA granted its chemotherapy agent doxorubicin, used primarily for live cancer an orphan drug status. The Orphan Drug Act was created to encourage and promote research for therapies of rare conditions and diseases that affect less than 200,000 a year in the United States.

Continue reading Delcath jumps 18% as its chemotherapy agent gets orphan drug status

Pfizer discontinues Phase III drug trial; stock continues to drag

Late yesterday, Pfizer (NYSE: PFE) announced the discontinuation of the SUN 1122 Phase III trial of Sutent. The drug is for treating colorectal cancer, and the study was terminated because it failed to achieve its primary end point in the study. An independent committee (the Data Monitoring Committee) found that adding sunitinib to the chemotherapy regimen FOLFIRI would be unable to demonstrate "a statistically significant improvement in the primary endpoint of progression-free survival compared to FOLFIRI alone."

The company's vice president of Clinical Development and Medical Affairs Dr. Mace Rothenberg noted, "We are disappointed with this result, but trial successes and failures are an integral part of cancer drug development and contribute to a growing body of knowledge on improving patient care."

Continue reading Pfizer discontinues Phase III drug trial; stock continues to drag

Despite earlier skepticism Dendreon (DNDN) proves itself -- shares soar

Dendreon Corp. (NASDAQ: DNDN) shares more than tripled today soaring from a previous close of $7.30 to $22.10. By noon DNDN traded up over 130% to around $17 a share. The company reported this morning that its experimental prostate cancer treatment, Provenge, was significantly successful in prolonging patient survival. This may clear the way for the long-awaited regulatory approval for the drug.

Dendreon plans to submit additional information to the FDA in the fourth quarter as part of its new drug application, meaning approval could come with six months, by mid- 2010.

Continue reading Despite earlier skepticism Dendreon (DNDN) proves itself -- shares soar

Steve Jobs blames cancer rumors on hedge funds!

Back in June, pancreatic cancer survivor and Apple (NASDAQ: AAPL) CEO Steve Jobs appeared at a conference appearing excessively thin and out of it, spurring rumors that Jobs was sick, possibly with another occurrence of cancer.

Joe Nocera reports that Jobs is now blaming the rumors on "hedge funds with a big short position in Apple."

Color me unconvinced. When a high-profile cancer survivor appears gaunt and sickly, there is no need for a nefarious conspiracy to spur questions about his health. Nocera has an interesting theory: "I think he likes having half the world wondering about his health. I think he likes the fact that Bloomberg accidentally put his obituary on the Web. It's a lovely reminder about just how important he is in the culture. It means half the world is spending time thinking about, well, him. Far more than anyone in hedge fund land, he himself was most responsible for the rumors, by acting so absurdly secretive. His narcissism isn't pretty, but it sure is effective."

Continue reading Steve Jobs blames cancer rumors on hedge funds!

Can cancer drugs help pharma sales?

Almost everyone these days has encountered cancer in one way or another. While the rate of cancer incidence has stabilized to declined since the early 1990s and, with newer and better treatments as well as early detection, cancer death rates have also declined, the war on cancer is still far from won.

It is no surprise, then, that a few days ago, IMS Health (NYSE: RX) -- a provider of market intelligence to the pharmaceutical and healthcare industries -- said that cancer drugs sales will nearly double by the year 2012. Assuming a compound growth rate of 12-15% a year, sales will grow from $48 billion in 2008 to $80 billion by 2012.

The main contributors to growth, according to the study, are an increasing number of patients on chemotherapy, not just in major markets but in emerging markets, too, as well as longer treatment periods for growing numbers of patients. Also fueling growth are the increased use of targeted therapeutic agents, along with first-time innovations coming to the market. Expensive new biotechnology drugs, and the increasing use of combination therapies that contribute to the exploding cost of treatment will also fuel cancer drugs sales growth.

The overall pharmaceutical market grew at a 6.4% pace in 2007, meaning that with its double-digit growth rate, the cancer drug market -- today contributing 17% to global pharmaceutical sales -- will only represent a greater proportion and emphasis. Of course, there will be factors moderating growth, such as drugs losing exclusivity and financial constraints of payers.

Cancer-fighting drugs can reach the market twice as fast as the average medicine, and companies can charge as much as $50,000 for a single course of treatment. It is no surprise then that with more and more drugs coming off patent many pharma companies are turning their attention to cancer. But can it save them?

Continue reading Can cancer drugs help pharma sales?

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Last updated: February 11, 2012: 05:56 AM

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