MOST NOTEWORTHY: CyberSource, Century Casinos, Spectrum Pharm and Winnebago were today's noteworthy upgrades:

• JMP Securities upgraded shares of CyberSource (NASDAQ: CYBS) to Market Outperform from Market Perform citing valuation, positive management comments regarding BidPay, and incrementally positive industry checks on its fraud product.
  
• Brean Murray upgraded shares of Century Casinos (NASDAQ: CNTY) to Buy from Hold based on continued progress at recently opened properties, reduced Street expectations, and potential catalysts.
  
• Brean Murray also upgraded Spectrum Pharmaceuticals (NASDAQ: SPPI) to Buy from Hold. The firm is highly confident that Spectrum's ozarelix will demonstrate similar efficacy and safety in the current U.S. Phase IIb trial and expects statistical significant. The firm expects Ph III initiations by year-end 2007 and Ph IIb data to be released on 2Q08.
  
• Winnebago Industries (NYSE: WGO) was upgraded to Outperform from Sector Perform at RBC Capital. The firm expects Winnebago to begin to post better earnings from more favorable mix and pricing in the 2008 model year.

OTHER UPGRADES:

• Merrill Lynch upgraded Cardinal Health (NYSE: CAH) to Buy from Neutral.
  
• Goldman upgraded shares of US Airways (NYSE: LCC) to Buy from Neutral.
  
• Avocent Corporation (NASDAQ: AVCT) was upgraded to Accumulate from Source the Funds at Think Equities.
  
• Collins Stewart raised Cyberonics (NASDAQ: CYBX) to Buy from Market Perform.

MOST NOTEWORTHY: The biotech sector, WESCO International, Wyndham and Century Casinos were today's noteworthy initiations:

• BMO Capital initiated coverage on Arena Pharmaceuticals Inc. (NASDAQ: ARNA) and Gilead Sciences Inc. (NASDAQ: GILD) with Outperform ratings and a $16 target and $51 target and Celgene Corp. (NASDAQ: CELG) and Genentech Inc. (NYSE: DNA) with Market Perform ratings and a $69 target and $85 target.
  
• CIBC initiated shares of WESCO International Inc. (NYSE: WCC) with a Sector Outperformer rating and $46 target. The firm believes lower estimates are already priced into shares and that the company's operating initiatives increase the chances for more stable margins in this environment.
  
• Deutsche Bank started shares of Wyndham Worldwide Corp. (NYSE: WYN) with a Buy rating and $41 target. The firm believes stability of the timeshare industry, international expansion and improved transparency will serve as catalysts for shares.
  
• Century Casinos Inc. (NASDAQ: CNTY) was initiated at Nollenberger with a Neutral rating, citing the underperformance of new properties and concerns from the smoking ban in Colorado; however, the firm believes the company is headed in the right direction.

OTHER INITIATIONS:

• Soleil started shares of Sunoco Inc. (NYSE: SUN) and Valero Energy Corp. (NYSE: VLO) with Buy ratings and targets of $96 and $88, and initiated shares of Tesoro Corp. (NYSE: TSO) with a Hold rating and $55 target.
  
• Rodman & Renshaw started shares of Labopharm Inc. (NASDAQ: DDSS) with a Market Perform rating.
  
• UBS resumed coverage on Kroger Co. (NYSE: KR) with a Buy rating and $34 target.

MOST NOTEWORTHY: Sonic Automotive (SAH), Hawaiian Electric (HE), AstraZeneca (AZN), AMB Property (AMB) and ProLogis (PLD) were today's noteworthy downgrades:

• Goldman downgraded Sonic Automotive (NYSE: SAH) to Neutral from Buy on valuation.

• Hawaiian Electric (NYSE: HE) was cut to Underweight from Equal Weight at Lehman based on valuation and the regulatory environment.

• AstraZeneca (NYSE: AZN) was downgraded to Equal Weight from Overweight at MorganStanley based on the reduced buyback, the $1.6B restructuring charge and potential for Nexium generics in Europe.

• Citigroup cut AMB Property (NYSE: AMB) and ProLogis (NYSE: PLD) to Sell from Hold citing the tight capital markets and the impact on costs for the downgrades...

OTHER DOWNGRADES:

• JP Morgan downgraded D.R. Horton (NYSE: DHI) to Neutral from Overweight.

• Roth Capital downgraded Century Casinos (NASDAQ: CNTY) to Hold from Buy.

• Keybanc downgraded shares of Diebold (NYSE: DBD) to Hold from Buy.

• DA Davidson cut Sunrise Senior Living (NYSE: SRZ) to Sell from Neutral.

Analyst summaries provided by TheFlyOnTheWall.com (subscription required).

MOST NOTEWORTHY: RadioShack Corp (RSH), Juniper Networks, Inc (JNPR), H.B. Fuller Co (FUL) and Sepracor Inc (SEPR) were today's more notable downgrades:

• Morgan Stanley downgraded RadioShack (NYSE: RSH) to Underweight from Equal-Weight on concerns over the company's wireless fundamentals and top-line growth.

• Juniper Networks (NASDAQ: JNPR) was downgraded to Strong Sell from Buy at Matrix USA. The firm sees downside to the intrinsic value calculation of $12 given the company's deteriorating fundamentals.

• H.B. Fuller Co (NYSE: FUL) was cut to Sell from Hold at Gabelli following a meeting with management to reflect the recent management exists and the broker's expectation for a challenging first-half of 2007.

• Sepracor (NASDAQ: SEPR) was cut to Underperform from Market Perform at Friedman Billings, as the firm believes generic availability of Ambien may be a bigger challenge to Seprecor's Lunesta than investors expect.

OTHER DOWNGRADES:

• Jackson Hewitt Tax Service Inc (NYSE: JTX) was cut to Underweight from Market Weight at Thomas Wiesel as they believe the potential near-term competitive trends coupled with potential issues with rising financial product contribution will weigh on valuation.

• Bear Stearns cut Cerner Corp (NASDAQ: CERN) to Peer Perform from Outperform.

• Matrix USA downgraded InfoSpace, Inc (NASDAQ: INSP) to Hold from Buy on valuation.

• Prudential cut Unilever plc (NYSE: UL) to Neutral from Overweight.

• Breen Murray downgraded Century Casinos, Inc (NASDAQ: CNTY) to Hold from Buy.

• Cowen downgraded PeopleSupport, Inc (NASDAQ: PSPT) to Neutral from Outperform based on near-term visibility concerns.

Analyst summaries provided by TheFlyOnTheWall.com (subscription required).

MOST NOTEWORTHY: The Small Cap BioTech sector top today's small list of initiations.

• The Bank of America initiated five companies within the Small Cap BioTech sector:
• Myriad Genetics, Inc. (NASDAQ:MYGN), Array BioPharma, Inc. (NASDAQ:ARRY), Nuvelo, Inc. (NASDAQ:NUVO) and Keryx BioPharmaceuticals Inc (NASDAQ:KERX) with Buy ratings
• and Dendreon Corp (NASDAQ:DNDN) with a Neutral rating.

OTHER INITIATIONS:

• Fiserv, Inc. (NASDAQ:FISV) was resumed with a Market Perform at Wachovia on valuation
• and Century Casinos, Inc. (NASDAQ:CNTY) was initiated with a Hold at Morgan Joseph on valuation.

Analyst summaries provided by TheFlyOnTheWall.com (subscription required).