Google, Inc.'s (NASDAQ: GOOG) YouTube, the online video juggernaut that has more brand recognition than most things online or offline, could be just that -- brand recognition. It sure hasn't made Google loads of cash since the billion-dollar acquisition a few years back. Since then, YouTube has become a behemoth. Just like in Google's case with many of its products, though, it's now one of many products that is having trouble finding a revenue stream that's sustainable.

Analyst upgrades:

• Oppenheimer upgraded Genzyme (NASDAQ: GENZ) to Outperform from Perform on expectations that upcoming regulatory events, mainly approvals of Mozobil and 2,000L Myozyme, will serve as positive catalysts.
  
• Ladenburg analyst Dick Bove raised Bank of New York (NYSE: BK) to Buy from Neutral as he now believes the Russian lawsuit is turning in the bank's favor and is no longer a significant risk.
  
• Societe Generale upgraded UBS (NYSE: UBS) to Buy from Hold on valuation and the company's deal with the Swiss government.
  
• Bed Bath & Beyond (NASDAQ :BBBY) was upgraded to Market Perform from Underperform at Friedman Billings.
  
• RC2 Corp (NASDAQ: RCRC) was lifted at Wachovia to Outperform from Market Perform.
  
• Cintas (NASDAQ: CTAS) was upgraded to Hold from Sell at Citigroup.

Analyst downgrades:

Analyst upgrades:

• William Blair upgraded Parexel (NASDAQ: PRXL) to Outperform from Market Perform on increased conviction in the company's earnings growth outlook following channel checks.
  
• Friedman Billings upgraded UDR Inc (NYSE: UDR) to Outperform from Market Perform and raised its target to $22 from $26 citing the company's approximate 8% implied cap rate on is vastly improved apartment portfolio.
  
• Citigroup upgraded Abercrombie & Fitch (NYSE: ANF) to Hold from Sell on valuation as they believe weak fundamentals are now priced into the stock.
• Goldman upgraded Portland General Electric (NYSE: POR) to Buy from Neutral and added shares to the Conviction Buy List.
  
• StellarOne (NASDAQ: STEL) and Union Bankshares (NASDAQ: UBSH) were upgraded to Neutral from Underperform at Baird.
  
• Bernstein upgraded DISH Network (NASDAQ: DISH) to Market Perform from Underperform.

Analyst downgrades:

• Deutsche Bank downgraded Align Tech (NASDAQ: ALGN) to Hold from Buy as they believe macroeconomic pressures will limit the company's ability to reach longer term growth expectations. Align's target was lowered to $8 from $14.
  
• Jefferies downgraded shares of Advanced Medical (NYSE: EYE) to Underperform from Buy and lowered its target to $9 from $28 following the company's lowered guidance as they believe macroeconomic pressures affecting LASIK volumes and the unanticipated slowdown in lens care should put continued pressure on the stock.
  
• ThinkPanmure expects the macro slowdown and credit crunch to slow Intel's (NASDAQ: INTC) growth and IT capex spending. The firm downgraded shares to Sell from Buy, lowered its 2009 EPS estimate to $1.01 from $1.35, vs. consensus of $1.46, and cut Intel's target to $12 from $24.
• MGM Mirage (NYSE: MGM) was lowered to Neutral from Positive at Susquehanna.
  
• Charles River Labs (NYSE: CRL) was downgraded at William Blair to Market Perform from Outperform.
  
• Deutsche Bank cut Heinz (NYSE: HNZ) and MasterCard (NYSE: MA) to Hold from Buy.

Analyst initiations:

• Old Second Bancorp (NASDAQ: OSBC) was initiated with a Market Perform rating and $17 target at Keefe Bruyette. The firm believes the company's exposure to strong markets should generate above-average returns.
  
• Susquehanna assumed Affiliated Computer (NYSE: ACS) with a Positive rating and $55 target and is positive on the company's low levels of customer concentration and high levels of geographic diversification.
  
• Cowen resumed coverage of AnnTaylor (NYSE: ANN) with a Neutral rating, citing the company's share loss to competitors and top-line weakness..
• MetLife (NYSE: MET) was assumed with an Overweight rating at Morgan Stanley.
  
• JMP Securities initiated HFF Inc (NYSE: HF) with a Market Perform rating.
  
• Genpact (NYSE: G) was initiated at Susquehanna with a Neutral rating.

MOST NOTEWORTHY: Spirit Aerosystems, Genpact and SEI Investments were today's noteworthy initiations:

• Friedman Billings believes Spirit Aerosystems (NYSE: SPR) is well-positioned on key aircraft platforms and has significant revenue visibility. The firm started shares with an Outperform rating and $33 target.
  
• Baird is positive on Genpact's (NYSE: G) recurring, non-discretionary revenue, strong growth in Global Client revenue, market leading position; shares were assumed with an Outperform rating and $16 target.
  
• SEI Investments (NASDAQ: SEIC) was initiated with a Market Perform rating and $27 target at Keefe Bruyette, as they are cautious in the near-term due to industry headwinds.

OTHER INITIATIONS:

• Merrill Lynch initiated Sirius Satellite (NASDAQ: SIRI) with a Sell rating.
  
• Lehman started Tiffany & Co (NYSE: TIF) with an Overweight rating and $52 target.
  
• Oppenheimer initiated Cavium Networks (NASDAQ: CAVM) with a Perform rating.

MOST NOTEWORTHY: Staples, Office Depot, GlobalSCAPE and CytRx were today's noteworthy initiations:

• Jefferies initiated shares of Staples Inc (NASDAQ: SPLS) with a Hold rating and $22-$24 target. The firm finds the current valuation fair given the increased risk of excess store growth in the industry, increased promotional activity and deceleration of employment growth.
  
• Jefferies expects shares of Office Depot Inc (NYSE: ODP) to trade sideways given the company's accelerating store growth, greater promotional activity and execution issues. The firm resumed coverage with a Hold rating and $22-$24 target.
  
• Soleil started shares of GlobalSCAPE Inc (AMEX: GSB) with a Buy rating and $12 target, as they believe the company has the opportunity to grow revenues around 35%-40% annually and is an attractive acquisition candidate for suitors who address the corporate networking infrastructure marketplace.
  
• Cytrx Corporation (NASDAQ: CYTR) was initiated with a Buy rating and $6 target at Oppenheimer, as they are optimistic regarding the market potential of arimoclomol in amyotrophic lateral sclerosis and sees several catalysts approaching over the next 12-18 months.

OTHER INITIATIONS:

• Deutsche Bank started shares of Alliance Imaging Inc (NYSE: AIQ) and Pediatrix Medical Group Inc (NYSE: PDX) with Hold ratings and target of $10.50 and $70, respectively.
  
• Credit Suisse started shares of Accenture Ltd (NYSE: ACN), Genpact Limited (NYSE: G) and Cognizant Technology Solutions Corporation (NASDAQ: CTSH) with Outperform ratings and targets of $50, $20 and $53, respectively.

MOST NOTEWORTHY: Sigma Designs, Satyam and Genpact were today's noteworthy initiations:

• Deutsche Bank initiated shares of Sigma Designs (NASDAQ: SIGM) with a Buy rating and $62 target, as they believe the company can maintain its leadership position in the fast-growing IPTV and high-def DVD markets. Baird said Sigma's IPTV momentum is accelerating, Blu-ray demand in strong, and Ultrawideband is the next growth opportunity. The firm resumed coverage with an Outperform rating.
  
• Banc of America started shares of Satyam Computer Services (NYSE: SAY) with a Neutral rating and $39 target on valuation, as they believe better value exists in peers Cognizant Technology (NASDAQ: CTSH) and Infosys Technologies (NASDAQ: INFY).
  
• UBS initiated Genpact (NYSE: G) with a Neutral rating and $18 target on valuation.

OTHER INITIATIONS:

• Goldman resumed coverage of HealthSpring (NYSE: HS) with a Neutral rating and $23 target.
  
• Wachovia initiated Gentiva Health (NASDAQ: GTIV) with an Outperform rating.